My goal is 5 mg per day, but I am not very disciplined. I have seen visible improvements on my skin and teeth after just 2 weeks. As I recall, wgr had good results with 15 mg daily (Carlson 5 mg, 3 times per day.) If you have osteoporosis, you may want to take more than I do. The bottom line is that they found 1.5 mg daily to be effective in carboxylating osteocalcin. The study provided good news: We do not need to take 45 mg of Mk4 per day to get results. For correcting osteopenia, I decided on 1 to 5 mg.Īlthough there were many studies using the pharmaceutical dosage of 45 mg, Juliet pointed out a relatively recent article, published in 2009 “Effect of Low Dose Vitamin K2 (Mk-4) supplementation on Bio-Indices …” by Koitaya et al. Each of us needs to decide what's best, depending on the severity of the bone loss. And, you're correct that some doctors do not believe in supplements. I am conservative, being sensitive to medication.
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